diff --git a/.github/workflows/cmake_build.yml b/.github/workflows/cmake_build.yml
index 19693908f..c0dd086d7 100644
--- a/.github/workflows/cmake_build.yml
+++ b/.github/workflows/cmake_build.yml
@@ -136,6 +136,14 @@ jobs:
         export WXWIN="${WXWIN//\\//}"
 
         # Configure Audacity
+        #
+        # The wxWidgets_USE_REL_AND_DBG is needed because,
+        # on Github, we only build the Release version of
+        # wxWidgets and the FindwxWidgets CMake module
+        # defaults to looking for both.  If either of them
+        # isn't found, then it doesn't provides the required
+        # library information.  This is only a concern for
+        # Windows.
         cmake -S . \
               -B build \
               -G "${{matrix.config.generator}}" \
diff --git a/cmake-proxies/mod-null/CMakeLists.txt b/cmake-proxies/mod-null/CMakeLists.txt
index aa55e4f9a..bb9b1e417 100644
--- a/cmake-proxies/mod-null/CMakeLists.txt
+++ b/cmake-proxies/mod-null/CMakeLists.txt
@@ -19,6 +19,16 @@ list( APPEND INCLUDES
       ${TARGET_ROOT}
 )
 
+list( APPEND DEFINES
+   PRIVATE
+      # This is needed until the transition to cmake is complete and
+      # the Windows pragmas are removed from ModNullCallback.cpp.
+      # Without it, the wxWidgets "debug.h" will define __WXDEBUG__
+      # which then causes this module to emit library pragmas for the
+      # debug versions of wxWidgets...even if the build if for Release.
+      wxDEBUG_LEVEL=0
+)
+
 list( APPEND LIBRARIES
    PRIVATE
       Audacity
@@ -34,6 +44,7 @@ set_target_properties( ${TARGET}
 
 organize_source( "${TARGET_ROOT}" "" "${SOURCES}" )
 target_sources( ${TARGET} PRIVATE ${SOURCES} )
+target_compile_definitions( ${TARGET} PRIVATE ${DEFINES} )
 target_include_directories( ${TARGET} PRIVATE ${INCLUDES} )
 target_link_libraries( ${TARGET} PRIVATE ${LIBRARIES} )
 
diff --git a/cmake-proxies/mod-nyq-bench/CMakeLists.txt b/cmake-proxies/mod-nyq-bench/CMakeLists.txt
index afc4c11ba..7a6c2972e 100644
--- a/cmake-proxies/mod-nyq-bench/CMakeLists.txt
+++ b/cmake-proxies/mod-nyq-bench/CMakeLists.txt
@@ -19,6 +19,16 @@ list( APPEND INCLUDES
       ${TARGET_ROOT}
 )
 
+list( APPEND DEFINES
+   PRIVATE
+      # This is needed until the transition to cmake is complete and
+      # the Windows pragmas are removed from NyqBench.cpp.  Without
+      # it, the wxWidgets "debug.h" will define __WXDEBUG__ which
+      # then causes this module to emit library pragmas for the debug
+      # versions of wxWidgets...even if the build if for Release.
+      wxDEBUG_LEVEL=0
+)
+
 list( APPEND LIBRARIES
    PRIVATE
       Audacity
@@ -36,6 +46,7 @@ set_target_properties( ${TARGET}
 
 organize_source( "${TARGET_ROOT}" "" "${SOURCES}" )
 target_sources( ${TARGET} PRIVATE ${SOURCES} )
+target_compile_definitions( ${TARGET} PRIVATE ${DEFINES} )
 target_include_directories( ${TARGET} PRIVATE ${INCLUDES} )
 target_link_libraries( ${TARGET} PRIVATE ${LIBRARIES} )
 
diff --git a/cmake-proxies/mod-script-pipe/CMakeLists.txt b/cmake-proxies/mod-script-pipe/CMakeLists.txt
index ba98f1583..89690af82 100644
--- a/cmake-proxies/mod-script-pipe/CMakeLists.txt
+++ b/cmake-proxies/mod-script-pipe/CMakeLists.txt
@@ -22,6 +22,13 @@ list( APPEND INCLUDES
 list( APPEND DEFINES
    PRIVATE
       BUILDING_SCRIPT_PIPE
+
+      # This is needed until the transition to cmake is complete and
+      # the Windows pragmas are removed from ScripterCallback.cpp.
+      # Without it, the wxWidgets "debug.h" will define __WXDEBUG__
+      # which then causes this module to emit library pragmas for the
+      # debug versions of wxWidgets...even if the build if for Release.
+      wxDEBUG_LEVEL=0
 )
 
 list( APPEND LIBRARIES
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index b7f9c891d..8b4fb40af 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -1104,14 +1104,17 @@ set( PKGLIBDIR "${_LIBDIR}" )
 set( LIBDIR "${_LIBDIR}" )
 set( HAVE_GTK ${GTK_FOUND} )
 
-if( "${${_OPT}use_lame}" STREQUAL "local" )
-# Something is wrong in ExportMP3 when this is defined.
-# fix it and then uncomment this.
-#   set( DISABLE_DYNAMIC_LOADING_LAME YES )
-endif()
+# Do not define these for Windows or Mac until further testing
+# can be done against ExportMP3.cpp.  If either are defined, the
+# build will fail.
+if( NOT CMAKE_SYSTEM_NAME MATCHES "Windows|Darwin" )
+   if( "${${_OPT}use_lame}" STREQUAL "local" )
+      set( DISABLE_DYNAMIC_LOADING_LAME YES )
+   endif()
 
-if( "${${_OPT}use_ffmpeg}" STREQUAL "linked" )
-   set( DISABLE_DYNAMIC_LOADING_FFMPEG YES )
+   if( "${${_OPT}use_ffmpeg}" STREQUAL "linked" )
+      set( DISABLE_DYNAMIC_LOADING_FFMPEG YES )
+   endif()
 endif()
 
 if( CMAKE_SYSTEM_NAME MATCHES "Windows" )